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Catalog peptides

Angiotensin II, human

Name
Angiotensin II, human
Molecular structural formula
CAS Number
4474-91-3
Formula
C50H71N13O12
MW
1046.2
Sequence Shortening
DRVYIHPF (trifluoroacetate salt)
Sequence
H-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-OH (trifluoroacetate salt)
InChIKey
CZGUSIXMZVURDU-JZXHSEFVSA-N
Purity
≥98%
References
[1]: Hu C, Dandapat A, et,al. Angiotensin II induces capillary formation from endothelial cells via the LOX-1 dependent redox-sensitive pathway. Hypertension. 2007 Nov;50(5):952-7. doi: 10.1161/HYPERTENSIONAHA.107.096446. Epub 2007 Sep 24. PMID: 17893372. [2]: Crowley SD, Gurley SB, et,al. Angiotensin II causes hypertension and cardiac hypertrophy through its receptors in the kidney. Proc Natl Acad Sci U S A. 2006 Nov 21;103(47):17985-90. doi: 10.1073/pnas.0605545103. Epub 2006 Nov 7. PMID: 17090678; PMCID: PMC1693859.
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Angiotensin II is a hormone composed of eight amino acids, which is produced by the hydrolysis of angiotensin I through the action of angiotensin converting enzyme. This hormone is the core bioactive peptide in the renin-angiotensin system (RAS) and has a significant vasoconstrictive effect.