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Tumor Antigen Peptide (Customized)

Carbetocin

Name
Carbetocin
Molecular structural formula
CAS Number
37025-55-1
Formula
C45H69N11O12S
MW
988.2
Sequence Shortening
Unk-Y(Me)-IQNCPLG-NH2
Sequence
Unk-Tyr(Me) - Ile - GIn -Asn- Cys- Pro -Leu- Gly一NH2
InChIKey
NSTRIRCPWQHTIA-DTRKZRJBSA-N
DMSO solubility
≥ 31 mg/mL
Solubility in water
≥ 33.33 mg/mL
Purity
≥98%
References
[1]. Stella Chaviaras, et al. Assessing the antidepressant-like effects of carbetocin, an oxytocin agonist, using a modification of the forced swimming test. Psychopharmacology (Berl). 2010 May;210(1):35-43. [2]. Gerald Gimpl, et al. Binding domains of the oxytocin receptor for the selective oxytocin receptor antagonist barusiban in comparison to the agonists oxytocin and carbetocin. Eur J Pharmacol. 2005 Mar 7;510(1-2):9-16. [3]. David Feifel, et al. The effects of oxytocin and its analog, carbetocin, on genetic deficits in sensorimotor gating. Eur Neuropsychopharmacol. 2012 May;22(5):374-8.
Target
Oxytocin Receptor
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Carbitoxin is a nonapeptide analog prepared by chemical synthesis that has agonist properties, is able to penetrate the blood-brain barrier, and activate receptors within the central nervous system.