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Catalog peptides

Goralatide

Name
Goralatide
Molecular structural formula
CAS Number
120081-14-3
Formula
C20H33N5O9
MW
487.50
Sequence Shortening
Ac-SDKP
Sequence
Ac-Ser-Asp-Lys-Pro
InChIKey
HJDRXEQUFWLOGJ-UHFFFAOYSA-N
Purity
95%
References
[1].Renal protective effects of N-acetyl-Ser-Asp-Lys-Pro in deoxycorticosterone acetate-salt hypertensive mice. [2]. N-acetyl-Ser-Asp-Lys-Pro inhibits interleukin-1β-mediated matrix metalloproteinase activation in cardiac fibroblasts. [3]. The hemoregulatory peptide N-acetyl-Ser-Asp-Lys-Pro is a natural and specific substrate of the N-terminal active site of human angiotensin-converting enzyme.
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Gorelatide is a tetrapeptide compound derived from the body, with its nitrogen terminus acetylated. The substance is widely distributed in various tissues and body fluids of the human body, and is released from the precursor substance thymosin β4 through the hydrolysis of prolyl oligopeptidase (POP).