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Ornipressin

Name
Ornipressin
Molecular structural formula
CAS Number
3397-23-7
Formula
C45H63N13O12S2
MW
1042.19
Sequence Shortening
CYFQNCP-{Orn}-G-NH2 (Disulfide bridge: Cys1-Cys6)
Sequence
Cys-Tyr-Phe-Gln-Asn-Cys-Pro-{Orn}-Gly-NH2 (Disulfide bridge: Cys1-Cys6)
InChIKey
MUNMIGOEDGHVLE-LGYYRGKSSA-N
Solubility in water
75 mg/mL
Purity
≥98%
References
[1]. Fruhstorfer H, et al. Dose-response relation of ornipressin with regard to vasoconstriction in human skin. Br J Anaesth. 1994 Aug;73(2):220-4. [2]. De Kock M, et al. Ornipressin (Por 8): An efficient alternative to counteract hypotension during combined general/epidural anesthesia. Anesth Analg. 2000 Jun;90(6):1301-7.
Target
others
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Product details
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Ornipressin is a synthetic vasopressin analogue that replaces the arginine at position 8 of vasopressin with ornithine. This substance has a similar mechanism of action to felypressin, however, ornipressin has a more pronounced vasoconstrictive effect and acts more rapidly.