Ecallantide

A (265 species)

Adrenocorticotropic hormone Adrenomedullin Adrenorphin Angiotensin Adipokinetic Hormone AGRP Aquaporin-2 Allatostatin ANP Atriopeptin Antioxidant Antho-Rfamide Apelin Amylin Amyloid

B (44 species)

BNP Bradykinin

C (134 species)

CRF CGRP CCAP C-Reactive Protein C-Peptide CEA Cholecystokinin Cortistatin Conotoxin Cardiotoxin Calcitonin Casomorphin CREBtide Ceruletide CEF

D (42 species)

Deltorphin Dynorphin

E (116 species)

Exendin EGF Endomorphin Endorphin Endothelin Enkephalin Enterostatin Endokinin

F (25 species)

FGF Fibrinogen Fibrinopeptide Fibronectin Flu

G (123 species)

GM-CSF Gn-RH GHRP Glucagon Gp100 GPC3 Galanin GIP Gastrin Ghrelin Guanylin GAP

H (67 species)

HIV HCG Hypercalcemia Malignancy Factor HGH Hepatitis/HBV Histatin Helospectin

I (62 species)

IGF Insulin Inhibitor Influenza IL

K (13 species)

Kinase

L (45 species)

Laminin Leucokinin LH-RH Lipotropin LL - 37 Leptin

M (76 species)

MCH Melanocyte Protein Magainin MAGE MART-1 Mastoparan Myelin

N (115 species)

Neurotrophic factor Neuromedin Neurokinin Neuropeptide Natriuretic peptide

O (782 species)

Obestatin OVA Oxytocin Orexin others

P (138 species)

PACAP pTH Protease Activated Receptor Peptide YY PLP Procathepsin Pannexin Peptide YY Prolactin Pancreatic Polypeptide Probe

R (61 species)

RF amide Receptor RGD

S (187 species)

Substance P Salusin Saposin Sarafotoxin Secretin Somatostatin Substrate SH2 Domain Ligand

T (43 species)

TRH TNF Toxin B Tyrosinase Terlipressin

U (35 species)

Urocortin Urotensin

V (44 species)

VIP Vasopressin Valorphin

W (3 species)

Wwamide

X (4 species)

Xenopsin

Name Ecallantide	Molecular structural formula
Purity 95%
CAS Number 460738-38-9
Formula C305H442N88O91S8
MW 7053.81
Target Ser/Thr Protease
Sequence EAMHSFCAFKADDGPCRAAHPRWFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTRD (Disulfide bond:Cys1-Cys6, Cys2-Cys4, Cys3-Cys5)
Sequence Shortening Glu-Ala-Met-His-Ser-Phe-Cys-Ala-Phe-Lys-Ala-Asp-Asp-Gly-Pro-Cys-Arg-Ala-Ala-His-Pr o-Arg-Trp-Phe-Phe-Asn-Ile-Phe-Thr-Arg-Gln-Cys-Glu-Glu-Phe-Ile-Tyr-Gly-Gly-Cys-Glu_x005fGly-Asn-Gln-Asn-Arg-Phe-Glu-Ser-Leu-Glu-Glu-Cys-Lys-Lys-Met-Cys-Thr-Arg-Asp (Disu lfide bond:Cys1-Cys6, Cys2-Cys4, Cys3-Cys5)
InChIKey VBGWSQKGUZHFPS-BRUBJIIKSA-N
References [1]. Martello JL, et al. Ecallantide for treatment of acute attacks of hereditary angioedema. Am J Health Syst Pharm. 2012 Apr 15;69(8):651-7.