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Home / Peptide products / C (134 species) / CRF / CRF (6-33) (human, rat)
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CRF (6-33) (human, rat)
Name
CRF (6-33) (human, rat)
Molecular structural formula
Purity
≥95%
CAS Number
120066-38-8
Formula
C141H231N41O43S
MW
3220.73
Target
CRFR
Sequence
Ile-Ser-Leu-Asp-Leu-Thr-Phe-His-Leu-Leu-Arg-Glu-Val-Leu-Glu-Met-Ala-Arg-Ala-Glu-Gln-Leu-Ala-Gln-Gln-Ala-His-Ser
Sequence Shortening
ISLDLTFHLLREVLEMARAEQLAQQAHS
InChIKey
XHHPINGDTRCKNN-QZXFXOMNSA-N
References
[1]. S C Heinrichs, et al. Dissociation of arousal-like from anxiogenic-like actions of brain corticotropin-releasing factor receptor ligands in rats. Behav Brain Res. 2001 Jul;122(1):43-50. [ [2]. S C Heinrichs, et al. Selective stimulatory actions of corticotropin-releasing factor ligands on correlates of energy balance. Physiol Behav. 2001 Sep 1-15;74(1-2):5-13.
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Product details
Data download

CRF(6-33)(human) is a CRF binding protein (CRF-BP) ligand inhibitor. CRF(6-33)(human) competitively binds the CRF-BP but not the post-synaptic CRF receptors. CRF(6-33)(human) has anti-obesity effect.